Thomas Szyperski's Complete List of Publications
- Szyperski, T. and Schwerdtfeger, P. (1989) On the Stability of Trioxo(η5-Cyclopentadienyl) Compounds of Manganese, Technetium and Rhenium: An ab initio SCF Study. Angew. Chem. Int. Ed. Engl. 28, 1228-1231
- Neri, D., Szyperski, T., Otting, G., Senn, H. and Wüthrich, K. (1989) Stereospecific Nuclear Magnetic Resonance Assignments of the Methyl Groups of Valine and Leucine in the DNA-Binding Domain of the 434 Repressor by Biosynthetically Directed Fractional 13C Labeling. Biochemistry 28, 7510-7516. PMID:2692701
- Szyperski, T., Neri, D., Leiting, B., Otting, G. and Wüthrich, K. (1992) Support of 1H NMR Assignments In Proteins by Biosynthetically Directed Fractional 13C-labeling. J. Biomol. NMR 2, 323-334. PMID:1324756
- Szyperski, T., Güntert, P., Otting, G. and Wüthrich, K. (1992) Determination of Scalar Coupling Constants by Inverse Fourier Transformation of In-Phase Multiplets. J. Magn. Reson. 99, 552-560.
- Szyperski, T, Güntert. P., Stone, S. R. and Wüthrich, K. (1992) Nuclear Magnetic Resonance Solution Structure of Hirudin(1-51) and Comparison with Corresponding Three-dimensional Structures Determined Using the Complete 65-Residue Hirudin Polypeptide Chain. J. Mol. Biol. 228, 1193-1205. PMID:1335515
- Szyperski, T., Güntert, P., Stone, S. R., Tulinsky, A., Bode, W., Huber, R. and Wüthrich, K. (1992) Impact of Protein-Protein Contacts on the Conformation of Thrombin-bound Hirudin Studied by Comparison with the Nuclear Magnetic Resonance Solution Structure of Hirudin(1-51). J. Mol. Biol. 228, 1206-1211. PMID:1474586
- Wüthrich, K., Szyperski, T., Leiting, B. and Otting, G. (1992) Biosynthetic Pathways of the Common Proteinogenic Amino Acids Investigated by Fractional 13C Labeling and NMR Spectroscopy. Frontiers and New Horizons in Amino Acid research, 41-48.
- Szyperski, T., Wider, G., Bushweller, J. H. and Wüthrich, K. (1993) 3D 13C-15N-heteronuclear Two-spin Coherence Spectroscopy for Polypeptide Backbone Assignments in 13C-15N-double-labeled Proteins. J. Biomol. NMR 3, 127-132. PMID:8448432
- Szyperski, T., Luginbühl, P., Otting, G., Güntert, P. and Wüthrich, K. (1993) Protein Dynamics studied by Rotating Frame 15N Spin Relaxation Times. J. Biomol. NMR 3, 151-164. PMID:7682879
- Szyperski, T., Wider, G., Bushweller, J. H. and Wüthrich, K. (1993) Reduced Dimensionality in Triple-Resonance NMR Experiments. J. Am. Chem. Soc. 115, 9307-9308.
- Szyperski, T., Scheek, S., Johansson, J., Assmann, G., Seedorf, U. and Wüthrich, K. (1993) NMR Determination of the Secondary Structure and the Three-dimensional Polypeptide Backbone Fold of the Human Sterol Carrier Protein 2. FEBS Lett. 335, 18-26. PMID: 8243660
- Johansson, J., Szyperski, T., Curstedt, T. and Wüthrich, K. (1994) The NMR Structure of the Pulmonary Surfactant-Associated Polypeptide SP-C in an Apolar Solvent Contains a Valyl-Rich α-Helix. Biochemistry 33, 6015-6023. PMID:8180229
- Szyperski, T., Antuch, W., Schick, M., Betz, A., Stone, S. R. and Wüthrich, K. (1994) Transient Hydrogen Bonds Identified on the Surface of the NMR Solution Structure of Hirudin. Biochemistry 33, 9303-9310. PMID:8049231
- Ottiger, M., Szyperski, T., Luginbühl, P., Ortenzi, C., Luporini, P., Bradshaw, R. A. and Wüthrich, K. (1994) The NMR Solution Structure of the Pheromone Er-2 From the Ciliated Protozoan Euplotes raikovi. Protein Science 3, 1515-1526. PMID:7833811 PMCID: PMC2142943
- Szyperski, T., Pellecchia, M. and Wüthrich, K. (1994) 3D Hα/βCα/β(CO)NHN, a Projected 4D NMR Experiment for the Sequential Correlation of Polypeptide 1Hα/β,13Cα/β and Backbone 15N and 1HN Chemical Shifts. J. Magn. Reson. B 105, 188-191.
- Szyperski, T., Pellecchia, M., Wall, D., Georgopoulos, C. and Wüthrich, K. (1994) NMR Structure Determination of the Escherichia coli DnaJ Molecular Chaperone: Secondary Structure and Backbone Fold of the N-terminal Region (residues 2-108) Containing the Highly Conserved J Domain. Proc. Natl. Acad. Sci. USA 91, 11343-11347. PMID:7972061 PMCID: PMC45227
- Smith, P. E., van Schaik, R. C., Szyperski, T., Wüthrich, K. and van Gunsteren, W. F. (1995) Internal Mobility of the Basic Pancreatic Trypsin Inhibitor in Solution: A Comparison of NMR Spin Relaxation Measurements and Molecular Dynamics Simulations. J. Mol. Biol. 246, 356-365. PMID: 7532721
- Johansson, J., Szyperski, T. and Wüthrich, K. (1995) Pulmonary Surfactant-Associated Polypeptide SP-C in Lipid Micelles: CD Studies of Intact SP-C and NMR Secondary Structure Determination of Depalmitoyl-SP-C(1-17). FEBS Lett. 362, 261-265. PMID: 7729509
- Szyperski, T., Braun, D., Fernández, C., Bartels, C. and Wüthrich, K. (1995) A Novel Reduced-Dimensionality Triple-Resonance Experiment for Efficient Polypeptide Backbone Assignment, 3D CO HN N CA. J. Magn. Reson. B 108, 197-203.
- Szyperski, T. (1995) Biosynthetically Directed Fractional 13C-labeling of Proteinogenic Amino Acids. An Efficient Analytical Tool to Investigate Intermediary Metabolism. Eur. J. Biochem. 232, 433-448. PMID: 7556192
- Luginbühl, P., Szyperski, T. and Wüthrich, K. (1995) Statistical Basis for the Use of 13Cα Chemical Shifts in Protein Structure Determination. J. Magn. Reson. B 109, 229-233.
- Zerbe, O., Szyperski, T., Ottiger, M. and Wüthrich, K. (1996) Three-dimensional 1H-TOCSY-relayed ct-[13C,1H]-HMQC for Aromatic Spin System Identification in Uniformly 13C-labeled Proteins. J. Biomol. NMR 7, 99-106. PMID: 22911006
- Pellecchia, M., Szyperski, T., Wall, D., Georgopoulos, C. and Wüthrich, K. (1996) NMR Structure of the J-domain and the Gly/Phe-rich Region of the Escherichia Coli. DnaJ Chaperone. J. Mol. Biol. 260, 236-250. PMID: 8764403
- Szyperski, T., Braun, D., Banecki, B. and Wüthrich, K. (1996) Useful Information from Axial Peak Magnetization in Projected NMR Experiments. J. Am. Chem. Soc. 118, 8146-8147.
- Szyperski, T., Bailey, J. E. and Wüthrich, K. (1996) Detecting and Dissecting Metabolic Fluxes Using Biosynthetic Fractional 13C Labeling and Two-dimensional NMR Spectroscopy. Trends in Biotechnology 14, 453-459.
- Fernández, C., Szyperski, T., Bruyère, T., Ramage, P., Mösinger, E. and Wüthrich, K. (1997) NMR Solution Structure of the Pathogenesis-Related Protein P14a. J. Mol. Biol. 266, 576-593. PMID:9067611
- Pellecchia, M., Iwai, H., Szyperski, T. and Wüthrich, K. (1997) The 2D NMR Experiments H(C)CO2 and HCCO2 for Assignment and pH Titration of Carboxylate Groups in Uniformly 15N/13C-Labeled Proteins. J. Magn. Reson. 124, 274-278. PMID:9424317
- Sauer, U., Hatzimanikatis, V., Bailey, J. E., Hochuli, M., Szyperski, T. and Wüthrich, K. (1997) Metabolic Fluxes in Riboflavin-producing Bacillus subtilis. Nature Biotechnol. 15, 448-452. PMID: 9131624
- Szyperski, T., Fernández, C. and Wüthrich, K. (1997) Two-dimensional ct-HC(C)H-COSY for Resonance Assignments of Smaller 13C-labeled Biomolecules. J. Magn. Reson. 128, 228-232. PMID:9356277
- Szyperski, T., Ono, A., Fernández, C., Iwai, H., Tate, S., Wüthrich, K. and Kainosho, M. (1997) Measurement of 3JC2’P Scalar Couplings in a 17 kDa Protein Complex with 13C,15N-Labeled DNA Distinguishes the BI and BII Phosphate Conformations of the DNA. J. Am. Chem. Soc. 119, 9901-9902.
- Klimašauskas, S., Szyperski, T., Serva, S. and Wüthrich, K. (1998) Dynamic Modes of the Flipped-out Cytosine during HhaI Methyltransferase-DNA Interactions in Solution. EMBO J. 17, 317-324. PMID:9427765 PMCID: PMC1170382
- Szyperski, T., Fernández, C., Ono, A., Kainosho, M. and Wüthrich, K. (1998) Measurement of Deoxyribose 3JHH Scalar Couplings Reveals Protein Binding-Induced Changes in the Sugar Puckers of the DNA. J. Am. Chem. Soc. 120, 821-822.
- Szyperski, T., Fernández, C., Mumenthaler, C. and Wüthrich, K. (1998) Structure Comparison of Human Glioma Pathogenesis-Related Protein GliPR and the Plant Pathogenesis-related Protein P14a Indicates a Functional Link between the Human Immune System and a Plant Defense System. Proc. Natl. Acad. Sci. USA 95, 2262-2266. PMID: 9482873 PMCID: PMC19313
- Szyperski, T., Banecki, B., Braun, D. and Glaser, R. W. (1998) Sequential Resonance Assignment of Medium-sized 15N/13C-labeled Proteins with Projected 4D Triple Resonance NMR Experiments. J. Biomol. NMR 11, 387-405.
- Fernández, C., Szyperski, T., Ono, A., Iwai, H., Tate, S., Kainosho, M. and Wüthrich, K. (1998) NMR with 13C,15N-doubly-labeled DNA: the Antennapedia Homeodomain Complex with a 14-mer DNA Duplex. J. Biomol. NMR 12, 25-37. PMID: 9729786
- Szyperski, T. (1998) 13C-NMR, MS and Metabolic flux Balancing in Biotechnology Research. Q. Rev. Biophys. 31, 41-106. PMID: 9717198
- Weber, F. E., Dyer, J. H., López Garcia, F., Werder, M., Szyperski, T., Wüthrich, K. and Hauser, H. (1998) In Pre-sterol Carrier Protein 2 (SCP2) in Solution the Leader Peptide 1-20 is Flexibly Disordered and the Residues 21-143 Adopt the Same Globular Fold as in Mature SCP2. Cell. Mol. Life Sci. 54, 751-759. PMID: 9711242
- Szyperski, T., Vandenbussche, G., Curstedt, T., Ruysschaert, J.-M., Wüthrich, K. and Johansson, J. (1998) Pulmonary Surfactant-associated Polypeptide C in a Mixed Organic Solvent Transforms From a Monomeric α-helical State Into Insoluble β-sheet Aggregates. Protein Sci. 7, 2533-2540. PMID: 9865947 PMCID: PMC2143885
- Pervushin, K., Ono, A., Fernández, C., Szyperski, T., Kainosho, M. and Wüthrich, K. (1998) NMR Scalar Couplings Across Watson-Crick Base Pair Hydrogen Bonds in DNA Observed by Transverse Relaxation-Optimized Spectroscopy. Proc. Natl. Acad. Sci. USA 95, 14147-14151. PMID: 9826668 PMCID: PMC24341
- Fiaux, J., Andersson, C. I. J., Holmberg, N., Bülow, L., Kallio, P. T., Szyperski, T., Bailey, J. E. and Wüthrich, K. (1999) 13C NMR Flux Ratio Analysis of Escherichia coli Central Carbon Metabolism in Microaerobic Bioprocesses. J. Am. Chem. Soc. 121, 1407-1408.
- Szyperski, T., Götte, M., Billeter, M., Perola, E., Cellai, L., Heumann, H. and Wüthrich, K. (1999). NMR Structure of the Chimeric Hybrid Duplex r(gcaguggc)·r(gcca)d(CTGC) Comprising the tRNA-DNA Junction Formed During Initiation of HIV-1 Reverse Transcription. J. Biomol. NMR 13, 343-355. PMID: 10353196
- Szyperski, T., Glaser, R. W., Hochuli, M., Fiaux, J., Sauer, U., Bailey, J. E. and Wüthrich, K. (1999) Bioreaction Network Topology and Metabolic Flux Ratio Analysis by Biosynthetic Fractional 13C Labeling and Two-dimensional NMR Spectroscopy. Metabolic. Eng. 1, 189-197. PMID:10937933
- Hochuli, M., Patzelt, H., Oesterhelt, D., Wüthrich, K. and Szyperski, T. (1999) Amino Acid Biosynthesis in the Halophilic Archaeon Haloarcula hispanica. J. Bacteriol. 181, 3226-3237. PMID:10322026 PMCID: PMC93780
- Szyperski, T., Fernández, C., Ono, A., Wüthrich, K. and Kainosho, M. (1999) The 2D {31P} Spin-echo-difference Constant-time [13C, 1H]-HMQC Experiment for Simultaneous Determination of 3JH3’P and 3JC4’P in 13C-Labeled Nucleic Acids and Their Protein Complexes. J. Magn. Reson. 140, 491-494. PMID:10497056
- Fernández, C., Szyperski, T., Billeter, M., Ono, A., Iwai, H., Kainosho, M. and Wüthrich, K. (1999) Conformational Changes of the BS2 Operator DNA Upon Complex Formation with the Antennapedia Homeodomain Studied by NMR with 13C/15N-labeled DNA. J. Mol. Biol. 292, 609-617. PMID:10497025
- Sauer, U., Lasko, D. R., Fiaux, J., Hochuli, M., Glaser, R., Szyperski, T., Wüthrich, K. and Bailey, J. E. (1999) Metabolic Flux Ratio (METAFoR) Analysis of Genetic and Environmental Modulations of Escherichia coli Central Carbon Metabolism. J. Bacteriol. 181, 6679-6688. PMID:10542169 PMCID: PMC94132
- Lopez Garcia, F., Szyperski, T., Dyer, J. H., Choinowski, T., Seedorf, U., Hauser, H. and Wüthrich, K. (2000) NMR Structure of the Sterol Carrier Protein-2: Implications for the Biological Role. J. Mol. Biol. 295, 595-603. PMID:10623549
- Sauer, U., Szyperski, T and Bailey, J. E. (2000) Future Trends in Complex Microbial Reaction Studies. In: Barbotin, J.-N., Portais, J.-C. editors. NMR in Microbiology: Theory and Application. Norfolk (UK): Horizon Scientific Press. 479-490.
- Skalicky, J. and Szyperski, T (2000) Two-Dimensional NMR Spectroscopy. In: Barbotin, J.-N., Portais, J.-C. editors. NMR in Microbiology: Theory and Application. Norfolk (UK): Horizon Scientific Press. 157-166.
- Hochuli, M., Szyperski, T. and Wüthrich, K. (2000) Deuterium Isotope Effects on the Central Carbon Metabolism of Escherichia coli Cells Grown on a D2O-containing Minimal Medium. J. Biomol. NMR 17, 33-42. PMID:10909864
- Skalicky, J. J., Sukumaran, D. K., Mills, J. L. and Szyperski, T. (2000) Toward Structural Biology in Supercooled Water. J. Am. Chem. Soc. 122, 3230-3231.
- Montelione, G. T., Zheng, D., Huang, Y., Gunsalus, K. C. and Szyperski, T. (2000) Protein NMR Spectroscopy in Structural Genomics. Nature Struc. Biol. 7, 982-985. PMID: 11104006
- Frey, A. D., Fiaux, J., Szyperski, T., Wüthrich, K., Bailey, J. E., and Kallio, P. T. (2001) Dissection of Central Carbon Metabolism of Hemoglobin-Expressing Escherichia coli by 13C Nuclear Magnetic Resonance Flux Distribution Analysis in Microaerobic Bioprocesses. Appl. Environ. Microbiol. 67, 680-687. PMID: 11157231 PMCID: PMC92635
- Skalicky, J. J., Mills, J. L., Sharma, S. and Szyperski, T. (2001) Aromatic Ring-flipping in Supercooled Water: Implications for NMR-based Structural Biology of Proteins. J. Am. Chem. Soc. 123, 388-397. PMID:11456540
- Canonaco, F., Hess, T. A., Heri, S., Wang, T., Szyperski, T. and Sauer, U. (2001) Metabolic Flux Response to Phosphoglucose Isomerase Knock-out in Escherichia Coli and Impact of Overexpression of the Soluble Transhydrogenase UdhA. FEMS Microbiol. Lett. 204, 247-252. PMID:11731130
- Maaheimo, H., Fiaux, J., Cakar, Z. P., Bailey, J. E., Sauer, U. and Szyperski, T. (2001) Central Carbon Metabolism of Saccharomyces cerevisiae Explored by Biosynthetic Fractional 13C Labeling of Common Amino Acids. Eur. J. Biochem. 268, 2464-2479. PMID:11298766
- Emmerling, M., Dauner, M., Ponti, A., Fiaux, J., Hochuli, M., Szyperski, T., Wüthrich, K., Bailey, J. E. and Sauer, U. (2001) Metabolic Flux Response to Pyruvate Kinase Knockout in Escherichia Coli. J. Bacteriol. 184, 152-164. PMID:11741855 PMCID: PMC134756
- Dauner, M., Sonderegger, M., Hochuli, M., Szyperski, T., Wüthrich, K., Hohmann, H. P., Sauer, U. (2002) Intracellular Carbon Fluxes in Riboflavin-Producing Bacillus subtilis during Growth on Two-Carbon Substrate Mixtures. Appl. Environ. Microbiol. 68, 1760-1771. PMID:11916694 PMCID: PMC123836
- Monleón, D., Colson, K., Moseley, H. N. B., Anklin, C., Oswald, R., Szyperski, T. and Montelione, G. T. (2002) Rapid Analysis of Protein Backbone Resonance Assignments using Cryogenic Probes, a Distributed Linux-based Computing Architecture, and an Integrated Set of Spectral Analysis Tools. J. Struc. Func. Genomics 2, 93-101. PMID: 12836666
- Szyperski, T., Yeh, D. C., Sukumaran, D. K., Moseley, H. N. B. and Montelione, G. T. (2002) Reduced-dimensionality NMR Spectroscopy for High-Throughput Protein Resonance Assignment. Proc. Natl. Acad. Sci. USA 99, 8009-8014. PMID:12060747 PMCID: PMC123011
- Szymczyna, B. R., Pineda-Lucena, A., Mills, J. L., Szyperski, T. and Arrowsmith, C. (2002) 1H, 13C and 15N Resonance Assignments and Secondary Structure of the PWI Domain from SRm160 using Reduced Dimensionality NMR. J. Biomol. NMR 22, 299-300. PMID: 11991360
- Mills, J. L. and Szyperski, T. (2002) Protein Dynamics in Supercooled Water: The Search for Slow Motional Modes. J. Biomol. NMR 23, 63-67. PMID:12061719
- Szyperski, T. (2002) Strukturelle Genomik. Nachrichten aus der Chemie 50, 1128-1131.
- Xia, Y., Arrowsmith, C. H. and Szyperski, T. (2002) Novel Projected 4D Triple Resonance Experiments for Polypeptide Backbone Chemical Shift Assignment. J. Biomol. NMR 24, 41-50. PMID:12449417
- Gong, B., Zeng, H., Zhu, J., Yua, L., Han, Y., Cheng, S., Furukawa, M., Parra, R. D., Kovalevsky, A. Y., Mills, J. L., Skrzypczak-Jankun, E., Martinovic, S., Smith, R. D., Zheng, C., Szyperski, T. and Zeng, X. C. (2002) Creating Nanocavities of Tunable Sizes: Hollow Helices. Proc. Natl. Acad. Sci. USA 99, 11583-11588. PMID:12177422 PMCID: PMC129312
- Fiaux, J., Cakar, Z. P., Sonderegger, M., Wüthrich, K., Szyperski, T. and Sauer, U. (2003) Metabolic-Flux Profiling of the Yeasts Saccharomyces cerevisiae and Pichia stipitis. Eukaryotic Cell 2, 170-180. PMID:12582134 PMCID: PMC141173
- Kim, S. and Szyperski, T. (2003) GFT NMR, a New Approach to Rapidly Obtain Precise High-Dimensional NMR Spectral Information. J. Am. Chem. Soc. 125, 1385-1393. PMID: 12553842
- Daujotytė, D., Vilkaitis, G., Manelytė, L., Skalicky, J., Szyperski, T. and Klimašauskas, S. (2003) Solubility Engineering of the HhaI Methyltransferase. Protein Eng. 16, 295-301. PMID:12736373
- Liu, G., Mills, J. L., Hess, T. A., Kim, S., Skalicky, J. J., Sukumaran, D. K., Kupce, E., Skerra, A., Szyperski, T. (2003) Resonance Assignments for the 21 kDa Engineered Fluorescein-binding Lipocalin FluA. J. Biomol. NMR 27, 187-188. PMID: 12913418
- Aramini, J. M., Mills, J. L., Xiao, R., Acton, T. B., Wu, M. J., Szyperski, T. and Montelione, G. T. (2003) Letter to the Editor: Resonance Assignments for the Hypothetical Protein yggU from Escherichia coli. J. Biomol. NMR 27, 285-286. PMID:12975589
- Monleón, D., Chiang, Y., Aramini, J. M., Swapna, G. V. T., Macapagal, D., Gunsalus, K. C., Kim, S., Szyperski, T. and Montelione, G. T. (2004) Letter to the Editor: Backbone 1H, 15N and 13C Assignments for the 21 kDa Caenorhabditis elegans Homologue of ‘Brain-Specific’ Protein. J. Biomol. NMR 28, 91-92. PMID: 14739645
- Kim, S. and Szyperski, T. (2004) GFT NMR Experiments for Polypeptide Backbone and 13Cβ Chemical Shift Assignment. J. Biomol. NMR 28, 117-130. PMID:14755156
- Xu, D., Liu, G., Xiao, R., Acton, T., Goldsmith-Fischman, S., Honig, B., Montelione, G. T. and Szyperski, T. (2004) NMR Structure of the Hypothetical Protein AQ-1857 Encoded by the Y157 Gene from Aquifex aeolicus Reveals a Novel Protein Fold. Proteins 54, 794-796. PMID:14997575
- Liu, G., Sukumaran, D. K., Xu, D., Chiang, Y., Acton, T., Goldsmith-Fischman, S., Honig, B., Montelione, G. T. and Szyperski, T. (2004) NMR Structure of the Hypothetical Protein NMA1147 from Neisseria meningitidis Reveals a Distinct 5-Helix Bundle. Proteins 55, 756-758. PMID:15103637
- Herve du Penhoat, C., Atreya, H. S., Shen, Y., Liu, G., Acton, T. B., Xiao, R., Li, Z., Murray, D., Montelione, G. T. and Szyperski, T. (2004) The NMR Solution Structure of the 30S Ribosomal Protein S27e Encoded in Gene RS27_ARCFU of Archaeoglobus fulgidis Reveals a Novel Protein Fold. Protein Sci. 13, 1407-1416. PMID: 15096641 PMCID: PMC2286747
- Solà, A., Maaheimo, H., Ylönen, K., Ferrer, P. and Szyperski, T. (2004) Amino Acid Biosynthesis and Metabolic Flux Profiling of Pichia pastoris. Eur. J. Biochem. 271, 2462-2470. PMID:15182362
- Zamboni, N., Maaheimo, H., Szyperski, T., Hohmann, H.-P., and Sauer, U. (2004) The Phosphoenolpyruvate Carboxykinase also Catalyzes C3 Carboxylation at the Interface of Glycolysis and the TCA Cycle of Bacillus subtilis. Metabolic Eng. 6, 277-284. PMID: 15491857
- Shen, Y., Atreya, H. S., Xiao, R., Acton, T. B., Shastry, R., Ma, L., Montelione, G. T. and Szyperski, T. (2004) Letter to the Editor: Resonance Assignments for the 18 kDa Protein CC1736 from Caulobacter crescentus. J. Biomol. NMR 29, 549-550. PMID:15243193
- Moseley, H. N. B., Riaz, N., Aramini, J. M., Szyperski, T. and Montelione, G. T. (2004) A Generalized Approach to Automated NMR Peak List Editing: Application to Reduced Dimensionality Triple Resonance Spectra. J. Magn. Reson. 170, 263-277. PMID:15388090
- Atreya, H. S. and Szyperski, T (2004) G-matrix Fourier Transform NMR Spectroscopy for Complete Protein Resonance Assignment. Proc. Natl. Acad. Sci. USA 101, 9642-9647. PMID:15210958 PMCID: PMC470728
- Yuan, L., Zeng, H., Yamato, K., Sanford, A. R., Feng, W., Atreya, H. S., Sukumaran, D. K., Szyperski, T. and Gong, B. (2004) Helical Aromatic Oligoamides: Reliable, Readily Predictable Folding from the Combination of Rigidified Structural Motifs. J. Am. Chem. Soc. 126, 16528-16537. PMID:15600357
- Atreya, H. S. and Szyperski, T. (2005) Rapid NMR Data Collection. Methods Enzymol. 394, 78-108. PMID:15808218
- Huang, Y. J., Moseley, H., Baran, M. C., Arrowsmith, C., Powers, R., Tejero, R., Szyperski, T. and Montelione, G. T. (2005) An Integrated Platform for Automated Analysis of Protein NMR Structures. Methods Enzymol. 394, 111-140. PMID:15808219
- Shen, Y., Goldsmith-Fischman, S., Atreya, H. S., Acton, T., Ma, L., Xiao, R., Honig, B., Montelione, G. T. and Szyperski, T. (2005) NMR Structure of the 18 kDa Protein CC1736 From Caulobacter crescentus Identifies a Member of the “START” Domain Superfamily and Suggests Residues Mediating Substrate Specificity. Proteins 58, 747-750. PMID: 15616961
- Liu, G., Li, Z., Chiang, Y., Acton, T., Montelione, G. T., Murray, D. and Szyperski, T. (2005) High-quality Homology Models Derived from NMR and X-ray Structures of E. coli Proteins Y gdK and Suf E Suggest that All Members of the Y gdK/Suf E Protein Family are Enhancers of Cysteine Desulfurases. Protein Sci. 14, 1597-1608. PMID: 15930006 PMCID: PMC2253389
- Hervé du Penhoat, C., Li, Z., Atreya, H. S., Kim, S., Yee, A., Xiao, R., Murray, D., Arrowsmith, C. H. and Szyperski, T. (2005) NMR Solution Structure of Thermotoga maritima Protein TM1509 Reveals a Zn-metalloprotease-like Tertiary Structure. J. Struc. Func. Genomics 6, 51-62. PMID:15965736
- Szyperski, T. (2005). Protein NMR Spectroscopy. In: Meyers, R.A., editor. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Wiley-CH, Weinheim.
- Atreya, H. S., Eletsky, A. and Szyperski, T. (2005) Resonance Assignment of Proteins with High Shift Degeneracy Based on 5D Spectral Information Encoded in G2FT NMR Experiments. J. Am. Chem. Soc. 127, 4554-4555. PMID:15796503
- Shen, Y., Atreya, H. S., Liu, G. and Szyperski, T. (2005) G-matrix Fourier Transform NOESY-Based Protocol for High-Quality Protein Structure Determination. J. Am. Chem. Soc. 127, 9085-9099. PMID: 15969587
- Liu, G., Aramini, J., Atreya, H. S., Eletsky, A., Xiao, R., Acton, T., Ma, L. C., Montelione, G. T. and Szyperski, T. (2005) GFT NMR Based Resonance Assignment for the 21 kDa Human Protein UFC1. J. Biomol. NMR 32, 261. PMID:16132835
- Pineda-Lucena, A., Ho, C. S. W., Mao, D. Y. L., Sheng, Y., Laister, R. C., Muhandiram, R., Lu, Y., Seet, B. T., Katz, S., Szyperski, T., Penn, L. Z. and Arrowsmith, C. H. (2005) A Structure-based Model of the c-Myc/Bin1 Protein Interaction Shows Alternative Splicing of Bin1 and c-Myc Phosphorylation are Key Binding Determinants. J. Mol. Biol. 351, 182-194. PMID:15992821
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- Eletsky, A., Atreya, H. S., Liu, G. and Szyperski, T. (2005) Probing Structure and Functional Dynamics of (Large) Proteins with Aromatic Rings: L-GFT-TROSY (4,3)D HCCH NMR Spectroscopy. J. Am. Chem. Soc. 127, 14578-14579. PMID:16231903
- Szyperski, T., Mills, J. L., Perl, D. and Balbach, J. (2006) Combined NMR-observation of Cold Denaturation in Supercooled Water and Heat Denaturation Enables Accurate Measurement of ΔCp of Protein Unfolding. Eur. Biophys. J. 35, 363-366. PMID:16240113
- Szyperski, T. (2006) Principles and Application of Projected Multidimensional NMR Spectroscopy – G-matrix Fourier Transform NMR. Springer Series in Biophysics 10, (Advanced Techniques in Biophysics), 147-162.
- Liu, G., Shen, Y., Xiao, R., Acton, T., Ma, L. C., Joachimiak, A., Montelione, G. T. and Szyperski, T. (2006) NMR Structure of Protein yqbG from Bacillus subtilis Reveals a Novel α-Helical Protein Fold. Proteins 62, 288-291. PMID:16281282
- Szyperski, T. and Atreya, H. S. (2006) Principles and Applications of GFT Projection NMR Spectroscopy. Magn. Reson. Chem. 44, S51-S60. PMID:16826541
- Mukherjee, S., Muralidhar, D., Atreya, H. S., Szyperski, T., Jeromin, A., Sharma, Y. and Chary, K. V. R. (2006) 1H, 13C and 15N Chemical Shift Assignments for Neuronal Calcium Sensor-1, a Multi-functional Calcium-binding Protein. J. Biomol. NMR, 36, Suppl 1:48. PMID:16804767
- Lin, Y-C., Liu, G., Shen, Y., Bertonati, C., Yee, A., Honig, B., Arrowsmith, C. H., and Szyperski, T. (2007) NMR Structure of Protein PA2021 from Pseudomonas aeruginosa. Proteins 65, 767-770. PMID:16927296
- Solà, A., Jouhten, P., Maaheimo, H., Sànchez-Ferrando, F. and Szyperski, T., Ferrer, P. (2007) Metabolic Flux Profiling of Pichia pastoris Grown on Glycerol/methanol Mixtures in Chemostat Cultures at Low and High Dilution Rates. Microbiology 153, 281-290. PMID: 17185557
- Singarapu, K. K., Liu, G., Xiao, R., Bertonati, C., Honig, B., Montelione, G. T. and Szyperski, T. (2007) NMR Structure of Protein yjbR from Escherichia coli Reveals 'Double-wing' DNA Binding Motif. Proteins 67, 501-504. PMID:17266124
- Atreya, H. S., Garcia, E., Shen, Y. and Szyperski, T. (2007). J-GFT NMR for Precise Measurement of Mutually Correlated Nuclear Spin-Spin Couplings. J. Am. Chem. Soc. 129, 680-692. PMID:17227032
- Szyperski, T. (2007). Protein NMR Spectroscopy. In: Meyers, R.A., editor. Proteins. From Analytics to Structural Genomics. Wiley-CH, Weinheim.
- Singarapu, K. K., Xiao, R., Sukumaran, D. K., Acton, T., Montelione, G. T. and Szyperski, T. (2008) NMR structure of protein Cgl2762 from Corynebacterium glutamicum implicated in DNA transposition reveals a helix-turn-helix motif attached to a flexibly disordered leucine zipper. Proteins 70, 1650-1654. PMID:18175328
- Shen, Y. and Szyperski, T. (2008) Structure of the Protein BPTI Derived with the NOESY in Supercooled water: Validation and Refinement of Solution Structures. Angew. Chem. Int. Ed. Engl. 47, 324-326. PMID:17994654
- Singarapu, K. K., Xiao, R., Acton, T., Rost, B., Montelione, G. T. and Szyperski, T. (2008) NMR Structure of the Peptidyl-tRNA Hydrolase Domain from Pseudomonas syringae Expands the Structural Coverage of the Hydrolysis Domains of Class 1 Peptide Chain Release Factors. Proteins 71, 1027-1031. PMID:18247350
- Li, M., Yamato, K., Ferguson, J. S., Singarapu, K. K., Szyperski, T. and Gong, B. (2008) Sequence-specific, Dynamic Covalent Crosslinking in Aqueous Media. J. Am. Chem. Soc. 130, 491-500. PMID:18092773
- Zhang, Q., Atreya, H. S., Kamen, D. E., Girvin, M. E. and Szyperski, T. (2008) GFT Projection NMR Based Resonance Assignment of Membrane Proteins: Application to Subunit of E. coli F(1)F(0) ATP Synthase in LPPG Micelles. J. Biomol. NMR 40, 157-163. PMID:18273680
- Shen, Y., Lange, O., Delaglio, F., Rossi, P., Aramini, J. M., Liu, G., Eletsky, A., Wu, Y., Singarapu, K. K., Lemak, A., Ignatchenko, A., Arrowsmith, C. H., Szyperski, T., Montelione, G. T., Baker, D. and Bax, A. (2008) Consistent Blind Protein Structure Generation from NMR Chemical Shift Data. Proc. Natl. Acad. Sci. USA 105, 4685-4690. PMID:18326625 PMCID: PMC2290745
- Parish, D. M. and Szyperski, T. (2008) Simultaneously Cycled NMR Spectroscopy. J. Am. Chem. Soc. 130, 4925-4933. PMID:18338896
- Szyperski, T. (2008) On NMR-based Structural Proteomics. In: Structural Proteomics (Eds. J.L. Sussman and I. Silman), World Scientific Publishing, New York.
- Snyder, D. A., Ghosh, A., Zhang, F., Szyperski, T. and Bruschweiler, R. (2008) Z-matrix Formalism for Quantitative Noise Assessment of Covariance Nuclear Magnetic Resonance Spectra. J. Chem. Phys. 129, 104511. PMID:19044928 PMCID: PMC2669766
- Parish, D., Benach, J., Liu, G., Singarapu, K. K., Xiao, R., Acton, T., Su, M., Bansal, S., Prestegard, J. H., Hunt, J., Montelione, G. T. and *Szyperski, T. (2008) Protein Chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit Thioredoxin-like Structures Despite Lack of Canonical Thioredoxin Active Site Sequence motive. J. Struc. Funct. Genomics 9, 41-49. PMID:19039680 PMCID: PMC2850599 NIHMS180356
- Liu, G., Forouhar, F., Eletsky, A., Atreya, H. S., Aramini, J. M., Xiao, R., Huang, Y. J., Abashidze, M., Seetharaman, J., Liu, J., Rost, B., Acton, T., Montelione, G. T., Hunt, J. F. and Szyperski, T. (2009) NMR and X-RAY Structures of Human E2-like Ubiquitin-fold Modifier Conjugating Enzyme 1 (UFC1) Reveal Structural and Functional Conservation in the Metazoan UFM1-UBA5-UFC1 Ubiquination Pathway. J. Struc. Funct. Genomics 10:127-136. PMID:19101823 PMCID: PMC2850604 NIHMS180335
- Wu, Y., Ghosh, A. and Szyperski, T. (2009) Clean Absorption-Mode NMR Data Acquisition. Angew. Chem. Int. Ed. Engl. 48, 1479-1483. PMID:19140147 PMCID: PMC3018340 NIHMS148775
- Montelione, G. T., Arrowsmith, C. H., Girvin, M. E., Kennedy, M. A., Markley, J. L., Powers, R., Prestegard, J. H. and Szyperski, T. (2009) Unique Opportunities for NMR Methods in Structural Genomics. J. Struc. Funct. Genomics 10, 101-106. PMID: 19288278 PMCID: PMC2705713
- Yamamoto, S., Eletsky, A., Szyperski, T., Hay, J. and Ruyechan, W. T. (2009) Analysis of the Varicella-zoster Virus IE62 N-terminal Acidic Transactivating Domain and its Interaction with the Human Mediator Complex. J. Virol. 83, 6300-6305. PMID: 19357160 PMCID: PMC2687382
- Eletsky, A., Sukumaran, D. K., Xiao, R., Acton, T. B., Rost, B., Montelione, G. T. and Szyperski, T. (2009) NMR Structure of Protein YvyC from Bacillus subtilis Reveals Unexpected Structural Similarity Between Two PFAM families. Proteins 76, 1037-1041. PMID: 19455708 PMCID: PMC2735722 NIHMS130534
- Wu, Y., Ghosh, A. and Szyperski, T. (2009) Clean Absorption Mode NMR Data Acquisition Based on Time-Proportional Phase Incrementation. J. Struc. Funct. Genomics 10, 227-232. PMID: 19499349 PMCID: PMC2850597 NIHMS180353
- Mills, J. L., Liu, G., Skerra, A. and Szyperski, T. (2009) NMR Structure and Dynamics of the Engineered Fluorescein-binding Lipocalin FluA Reveal Rigidification of Beta-barrel and Variable Loops Upon Enthalpy-driven Ligand Binding. Biochemistry 11, 7411-7419. PMID: 19603796 PMCID: PMC2860743 NIHMS132867
- Sukumaran, D. K., Garcia, E., Hua, J., Tabaczynski, W., Odunsi, K., Andrews, C. and *Szyperski, T. (2009) Standard Operating Procedure For Metabonomics Studies of Blood Serum and Plasma Samples Using a 1H-NMR Micro-flow Probe. Magn. Reson. Chem. 47: S81-S85. PMID: 19688872
- Das, R., Andre, I., Shen, Y., Wu, Y., Lemak, A., Bansal, S., Arrowsmith, C. H., Szyperski, T. and Baker, D. (2009) Simultaneous Prediction of Protein Folding and Docking at High Resolution. Proc. Natl. Acad. Sci. USA 106, 18978-18983. PMID: 19864631 PMCID: PMC2770007
- Singarapu, K. K., Mills, J. L., Xiao, R., Acton, T., Punta, M., Fischer, M., Honig, B., Rost, B., Montelione, G. T. and Szyperski, T. (2010) Solution NMR structures of Proteins VPA0419 from Vibrio parahaemolyticus and yiiS from Shigella flexneri Provide Structural Coverage for Protein Domain Family PFAM 04175. Proteins 78, 779-784. PMID: 19927321 PMCID: PMC2860719 NIHMS156040
- Raman, S., Lange, O. F., Rossi, P., Tyka, M., Wang, X., Aramini, J., Liu, G., Ramelot, T. A., Eletsky, A., Szyperski, T, Kennedy, M. A., Prestegard, J., Montelione, G. T. and Baker, D. (2010) NMR Structure Determination for Larger Proteins using Backbone-only Data. Science 327:1014-1018. PMID: 20133520 PMCID: PMC2909653 NIHMS211856
- Montelione, G.T. and Szyperski, T. (2010) Advances in Protein NMR Provided by the NIGMS Protein Structure Initiative: Impact on Drug Discovery. Curr. Opin. Drug Discov. 13, 335-349. PMID: 20443167
- Love, J., Mancia, F., Shapiro, L., Punta, M., Rost, B., Girvin, M., Wang, D. N., Zhou, M., Hunt, J. F., Szyperski, T., Gouaux, E., MacKinnon, R., McDermott, A., Honig, B., Inouye, M., Montelione, G. T., and Hendrickson, W. A. (2010) The New York Consortium on Membrane Protein Structure Determination: a High-throughput Platform for Structural Genomics of Integral Membrane Proteins. J. Struct. Funct. Genomics 11, 191-199. PMID: 20690043 PMCID: PMC3099345 NIHMS233280
- Jha R.K., Leaver-Fay, A., Yin, S., Wu, Y., Butterfoss, G.L., Szyperski, T., Dokholyan, N.V., and Kuhlman, B. (2010) Computational Design of a PAK1 Binding Protein. J. Mol. Biol. 400, 257-270. PMID: 20460129 PMCID: PMC2903434 NIHMS212557
- Franks, W. T., Atreya, H. S., Szyperski, T. and Rienstra, C. M. (2010) GFT Projection NMR Spectroscopy for Proteins in the Solid State. J. Biomol. NMR 48, 213-223. PMID: 21052779 PMCID: PMC3058792 NIHMS265136
- Garcia, E., Andrews, C., Hua, J., Kim, H. L., Sukumaran, D. K., Szyperski, T. and Odunsi, K. (2011) Diagnosis of Early Stage Ovarian Cancer by 1H NMR Metabonomics of Serum Explored by Use of a Microflow NMR Probe. J. Proteome Res. 10: 1765-1771. PMID: 21218854 PMCID: PMC3074977 NIHMS275348
- Szyperski, T. and Montelione, G. T. (2011) Advances in NMR-based Structural Genomics. In: Biomolecular NMR Spectroscopy (Eds. A.J. Dingley and S.M. Pascal), IOS Press, Amsterdam.
- Eletsky, A., Ruyechan, W. T., Xiao, R., Acton, T. B., Montelione, G. T. and Szyperski, T. (2011) Solution NMR structure of MED25(391-543) Comprising the Activator-interacting Domain (ACID) of Human Mediator Subunit 25. J. Struct. Funct. Genomics 12:159-166. PMID: 21785987 PMCID: PMC3609412 NIHMS405907
- Szyperski, T. and Mills, J. L. (2011) NMR-based Structural Biology in Supercooled Water. J. Struct. Funct. Genomics 12:1-7. PMID: 21533787
- Ghosh, A., Wu, Y., He, Y. and Szyperski, T. (2011) Theory of Mirrored Time Domain sampling. J. Magn. Reson. 213:46-57. PMID: 21974999
- Der, B. S., Machius, M., Miley, M. J., Mills, J. L., Szyperski, T. and Kuhlman, B. (2012) Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer. J. Am. Chem. Soc. 134:375-85. PMID:22092237 PMCID: PMC3257401 NIHMS344730
- Eletsky, A., Acton, T. B., Xiao, R., Everett, J. K., Montelione, G. T. and Szyperski, T. (2012) Solution NMR Structures Reveal a Distinct Architecture and Provide First Structures for Protein Domain Family PF04536. J. Struct. Funct. Genomics 13:9-14. PMID:22198206 PMCID: PMC3609422 NIHMS405906
- Eletsky, A., Petrey, D., Zhang, Q. C., Lee, H. W., Acton, T. B., Xiao, R., Everett, J. K., Prestegard, J. H., Honig, B., Montelione, G. T. and Szyperski, T. (2012) Solution NMR Structures Reveal Unique Homodimer Formation by a Winged Helix-turn-helix Motif and Provide First Structures for Protein Domain Family PF10771. J. Struct. Funct. Genomics 13:1-7. PMID: 22223187 NIHMS405905
- Rosato A., Aramini, J. M., Arrowsmith C., Bagaria A., Baker D., Cavalli A., Doreleijers, J. F., Eletsky, A., Giachetti, A., Guerry, P., Gutmanas, A., Güntert, P., He, Y., Herrmann, T., Huang, Y.J., Jaravine, V., Jonker, H. R., Kennedy, M. A., Lange, O. F., Liu, G., Malliavin, T. E., Mani, R., Mao, B., Montelione, G. T., Nilges, M., Rossi, P., van der Schot, G., Schwalbe, H., Szyperski, T. A., Vendruscolo, M., Vernon, R., Vranken ,W. F., Vries, S.d., Vuister, G. W., Wu, B., Yang, Y., Bonvin, A. M. (2012) Blind Testing of Routine, Fully Automated Determination of Protein Structures from NMR Data. Structure 20:227-236. PMID: 22325772 PMCID: PMC3609704 NIHMS353547
- Murphy, G. S., Mills, J. L., Miley, M. J., Machius, M., Szyperski, T. and Kuhlman, B. (2012) Increasing Sequence Diversity with Flexible Backbone Protein Design: the Complete Redesign of a Protein Hydrophobic core. Structure 20:1086-1096. PMID: 22632833 PMCID: PMC3372604 NIHMS374182
- Thompson, J. M., Sgourakis, N. G., Liu, G., Rossi, P., Tang, Y., Mills, J. L., Szyperski, T., Montelione, G. T. and Baker, D. (2012) Accurate Protein Structure Modeling using Sparse NMR Data and Homologous Structure Information. Proc. Natl. Acad. Sci. USA 109:9875-9880. PMID:22665781 PMCID: PMC3382498
- Wu, Y., Punta, M., Xiao, R., Acton, T. B., Sathyamoorthy, B., Dey, F., Fischer, M., Skerra, A., Rost, B., Montelione, G. T. and Szyperski T. (2012) NMR Structure of Lipoprotein YxeF from Bacillus subtilis Reveals a Calycin Fold and Distant Homology with the Lipocalin Blc from Escherichia coli. PLoS One 7:e37404. PMID:22693626 PMCID: PMC3367933
- Eletsky, A., Jeong, M.Y., Kim, H., Lee, H.W., Xiao, R., Pagliarini, D.J., Prestegard, J.H., Winge, D.R., Montelione, G.T., Szyperski, T. (2012) Solution NMR Structure of Yeast Succinate Dehydrogenase Flavinylation Factor Sdh5 Reveals a Putative Sdh1 Binding Site. Biochemistry 51:8475-8477. PMID:23062074
- Reig, A.J., Pires, M.M., Snyder, R.A., Wu, Y., Jo, H., Kulp, D.W., Butch, S.E., Calhoun, J.R., Szyperski, T., Solomon, E.L., DeGrado, W.F. (2012) Alteration of the Oxygen-Dependent Reactivity of de novo Due Ferri Proteins. Nat. Chem. 4:900-906. PMID:23089864 PMCID: PMC3568993 NIHMS399993
- Rinaudo, P., Shen, S., Hua, J., Qian, S., Prabhu, U., Garcia, E., Cedars, M., Sukumaran, D., *Szyperski, T., Andrews, C. (2012) (1)H NMR Based Profiling of Spent Culture Media Cannot Predict Success of Implantation for Day 3 Human Embryos. J. Assist. Reprod. Genet. 29:1435-1442. PMID:23090745 PMCID: PMC3528870
- Atreya, H.S., Sathyamoorthy, B., Jaipuria, G., Beaumont, V., Varani, G., *Szyperski, T. (2012) GFT Projection NMR for Efficient (1)H/(13)C Sugar Spin System Identification in Nucleic Acids. J. Biomol. NMR 54:337-342. PMID:23192291 [PubMed in progress]
- Manning, K.A., Sathyamoorthy, B., Eletsky, A., Szyperski, T., Murkin, A.S. (2012) Highly Precise Measurement of Kinetic Isotope Effects Using 1H-Detected 2D [13C,1H]-HSQC NMR Spectroscopy. J. Am. Chem. Soc. 134:20589-20592. PMID:23215000
- Mills, J.L., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., *Szyperski, T. (2013) Solution NMR structure of the Helicase Associated Domain BVU_0683(627-691) from Bacteroides vulgatus Provides First Structural Coverage for Protein Domain Family PF03457 and Indicates Domain Binding to DNA. J Struct. Funct. Genomics 14: 19-24. PMID:23160728 NIHMS423432
- Sathyamoorthy, B., Singarapu, K.K., Garcia, A.E., *Szyperski, T. (2013) Protein Conformational Space Populated in Solution Probed with Aromatic Residual Dipolar (13)C-(1)H Couplings. ChemBioChem 14:684-688. PMID:23494854
- Pulavarti, S.V., He, Y., Feldmann, E.A., Eletsky, A., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., Kennedy, M.A., Szyperski, T. (2013) Solution NMR Structures Provide First Structural Coverage of the Large Protein Domain Family PF08369 and Complementary Structural Coverage of Dark Protochlorophyllide Oxidoreductase Complexes. J. Struct. Funct. Genomics 14: 119-126. PMID: 23963952
- Pulavarti, S.V., Eletsky, A., Lee, H.W., Acton, T.B., Xiao, R., Everett, J.K., Prestegard, J.H., Montelione, G.T., Szyperski, T. (2013) Solution NMR structure of CD1104D from Pathogenic Clostridium Difficile Reveals a Distinct a-Helical Architecture and Provides First Structural Representative of Protein Domain Family PF14203. J. Struct. Funct. Genomics 14: 155-160. PMID:24048810
- Stark, J.L., Copeland, J.C., Eletsky, A., Somerville, G.A., Szyperski, T., Powers, R. (2014) Identification of Low-molecular-weight Compounds Inhibiting Growth of Corynebacteria: Potential Lead Compounds for Anitibiotics. ChemMedChem 9:282-285. PMID:24403054
- Muppidi, A., Doi, K., Edwardraja, S., Pulavarti, S.V., Szyperski, T., Wang, H.G., Lin, Q. (2014) Targeted Delivery of Ubiquitin-conjugated BH3 Peptide-based Mcl-1 Inhibitors into Cancer Cells. Bioconj. Chem. 24:424-432. PMID:24410055
- Sathyamoorthy, B., Parish, D.M., Montelione, G.T., Xiao, R., Szyperski, T. (2014) Spatially Selective Heteronuclear Multiple-quantum (HMQC) Spectroscopy for Bio-molecular Studies. ChemPhysChem 15:1872-1879. PMID:24789578.
- Liu, G., Poppe, L., Aoki, K., Yamane, H., Lewis, J., Szyperski, T. (2014) High-quality NMR Structure of Human Anti-apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design.
PLoS One 9:e96521. PMID:24789074 - Xu, X., Pulavarti, S.V., Eletsky, A., Huang, Y.J., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., Szyperski, T. (2014) Solution NMR Structures of Homeodomains from Human Proteins ALX4, ZHX1, and CASP8AP2 Contribute the Structural Coverage of the Human Cancer Protein Interaction Network. J. Struct. Funct. Genomics 15: 201-207. PMID:24941917
- Pulavarti, S.V., Huang, Y.P., Pederson, K., Acton, T.B., Xiao, R. Everett, J.K., Prestegard, J.H., Montelione, G.T., Szyperski, T. (2014) Solution NMR Structures of Immunoglobulin-like Domains 7 and 12 from Obscurin-like Protein 1 Contribute the Structural Coverage of the Human Cancer Protein Interaction Network. J. Struct. Funct. Genomics 15: 209-214. PMID:24989974
- Eletsky, A., Michalska, K., Houliston, S., Zhang, Q., Daily, M.D., Xu, X., Cui, H., Yee, A., Lemak, A, Wu, B., Garcia, M., Burnet, M.C., Meyer, K.M., Aryal, U.K., Sanchez, O., Ansong, C., Xiao, R., Acton, T.B., Adkins, J.N., Montelione, G.T., Joachimiak, A., Arrowsmith, C.H., Savchenko, A., Szyperski, T., Cort, J.R. (2014) Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO. PloS One 9:e1010787.
- Pulavarti, S.V., Eletsky, A., Huang, Y.J., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., Szyperski, T. (2015) Polypeptide Backbone, Cb and Methyl Group Resonance Assignments of the 24 kDa Plectin Repeat Domain 6 from Human Protein Plectin. J. Biomol. NMR Assign. 9:135-138. PMID: 24722902
- Murphy, G.S., Sathyaoorthy, B., Der, B.S., Machius, M.C., Pulavarti, S.V., Szyperski, T., Kuhlman, B. (2015) Computational de novo Design of a Four-helix Bundle Protein-DND_4HB. Protein Sci. 24:434-445. PMID:25287625
- Everett, J., Tejero, R., Murthy, S.B., Acton, T.B., Aramini, J.M., Baran, M.C., Benach, J., Cort, J.R., Eletsky, A., Forouhar, F., Guan, R., Kuzin, A.P., Lee, H.W., Liu, G., Mani, R., Mao, B., Mills, J.L., Montelione, A.F., Pederson, K., Powers, R., Ramelot, T., Rossi, P., Seetharaman, J., Snyder, D., Swappna, G.V., Vorobiev, S.M., Wu, Y., Xiao, R., Yang. Y. Arrowsmith, C.H., Hunt, J., Kennedy, M.A., Prestegard, J.H., Szyperski, T., Tong, L., Montelione, G.T. (2016) A Community Resource of Experimental Data for NMR-X-ray Crystal Structure Pairs. Protein Sci.25:30-45. PMID 26293815
- Wu, X., Liu, R., Sathyamoorthy, B., Yamato, K., Liang, G., Shen, L., Ma, S., Sukumaran, D.K., Szyperski, T., Fang, W., He, L., Chen, X., Gong, B. (2015) Discrete Stacking of Aromatic Oligoamide Macrocycles. J. Am. Chem. Soc. 137:5879-5882. PMID:25909625
- Eletsky, A., Pulavarti, S.V., Beaumont, V., Gollnick, P., Szyperski, T. (2015) Solution NMR Experiment for Measurement of 15N-1H Residual Dipolar Couplings in Large Proteins and Supramolecular Complexes. J. Am. Chem. Soc. 137:11242-11245. PMID:26293598
- Turkoglu, O., Zeb, A., Graham, S., Szyperski, T., Szender, J. B., Odunsi, K., Szyperski, T., Bahado-Singh, R. (2016) Metabolomics of Biomarker discovery in Ovarian Cancer: a Systematic Review of the Current Literature. Metabolomics 12: 60.
- Connor, A. L., Hu, T., Detchou, C. S., Liu, R., Pulavarti, S. V., Szyperski, T., Lu, Z., Gong, B. (2016) Aromatic Oligoureas as Hosts for Anions and Cations. Chem. Commun. 52: 9905-9908. PMID: 27427283
- Jacobs, T. M., Williams, B., Williams, T., Xu, X., Eletsky, A., Federizon, J. F., Szyperski, T., Kuhlman, B. (2016) Design of Structurally Distinct Proteins Using Strategies Inspired by Evolution. Science 352: 687-690. PMID: 27151863
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- Guffy, S.L., Pulavarti S.V.S.R.K, Harrison, J., Fleming, D., Szyperski, T., Kuhlman, B. (2022) Inside-out Design of Zinc Binding Proteins with Non-native Backbones. Biochemistry, in press.