Christopher A. Loretz


Christopher A. Loretz.

Christopher A. Loretz


Christopher A. Loretz


Associate Professor
Director of MA Program
SUNY Chancellor's Award for Excellence in Teaching

Research Interests

Endocrine physiology

Contact Information

H509 Hochstetter Hall

Buffalo NY, 14260

Phone: (716) 645-4985


  • Ph.D., University of California, Los Angeles
  • Postdoctoral Research at University of California, Berkeley

Office Hours (Subject to Change)

  • Monday, Wednesday, Friday: 9:00 - 10:00am
  • Tuesday, Thursday: 8:30 - 9:30am

Research Summary

Current research centers on the physiology and evolutionary biology of salt and water balance in aquatic vertebrates. Specifically, laboratory projects explore the molecular physiology and evolution of the extracellular calcium-sensing receptor, endocrine mechanisms mediating adaptive changes in drinking and alimentary tract function, and the biophysics of epithelial ion transport in the fishes.

Selected Publications

  • Herberger, A.L., and Loretz, C.A. (2013). Morpholino oligonucleotide knockdown of the extracellular calcium-sensing receptor impairs early skeletal development in zebrafish. Comp. Biochem. Physiol. A: Molec. Integr. Physiol. 166: 470-481.[]
  • Herberger, A.L., and Loretz, C.A. (2013). Vertebrate extracellular calcium-sensing receptor evolution: selection in relation to life history and habitat. Comp. Biochem. Physiol. D: Genom. Proteom. 8: 86-94.[]
  • Loretz, C.A., Pollina, C., Herberger, A.L., Hyodo, S., and Takei, Y. (2012)Skeletal tissues in Mozambique tilapia (Oreochromis mossambicus) express the extracellular calcium-sensing receptor.Comp. Biochem. Physiol. A: Molec. Integr. Physiol. 163: 311-318[]
  • Herberger, A., and Loretz, C.A. (2011)Examining phylogenetic history of the extracellular calcium-sensing receptor: a key sensor in calcium homeostatic systems.Front. Endocrin. Conference Abstract: NASCE 2011: The inaugural meeting of the North American Society for Comparative Endocrinology []
  • Loretz, C.A., Pollina, C., Herberger, A.L., Hyodo, S., and Takei, Y. (2011)Skeletal tissues in tilapia express the extracellular calcium-sensing receptor.FASEB J. 25: 1048.1[]
  • Loretz, C.A. (2011)Rapid transitions among functional states support efficient osmoregulatory acclimation.Am. J. Physiol. Regul. Integr. Comp. Physiol. 300: R855-R857.[]
  • Takei, Y., and C.A. Loretz (2010)The gastrointestinal tract as an endocrine/neuroendocrine/paracrine organ: organization, chemical messengers and physiological targets.InFish Physiology, Volume 30, The Multifunctional Gut of Fish (M. Grosell, A.P. Farrell, and C.J. Brauner, Editors), Academic Press, San Diego, 2010, pp. 261-317.[ISBN 0-1237-4982-4]
  • Loretz, C.A., Pollina, C., Hyodo, S., and Takei, Y. (2009)Extracellular calcium-sensing receptor distribution in osmoregulatory and endocrine tissues of the tilapia.Gen. Comp. Endocrinol. 161: 216-228.[]
  • Loretz, C.A. (2008)Extracellular calcium-sensing receptors in fishes. Comp. Biochem. Physiol. A 149: 225-245.[]
  • Takei, Y., and Loretz, C.A. (2006)Chapter 8: Endocrinology.In: The Physiology of Fishes, 3rd Edition (D.H. Evans and J.B. Claiborne, Editors), CRC Press, Boca Raton, pp. 271-318.[ISBN 0-8493-2022-4]
  • Loretz, C.A., Pollina, C., Hyodo, S., Takei, Y., Chang, W., and Shoback, D. (2004)cDNA cloning and functional expression of a Ca2+-sensing receptor with truncated carboxyterminal tail from the Mozambique tilapia (Oreochromis mossambicus).J. Biol. Chem. 279: 53288-53297.[]
  • Loretz, C.A. (Editor) (2002)Looking Beyond the Borders: A Project Directors Handbook of Best Practices for International Research Experiences for Undergraduates, 102 pp.[]
  • Loretz, C.A., and Pollina, C. (2000)Natriuretic peptides in fish physiology.Comp. Biochem. Physiol. A 125: 169-187.[]
  • Loretz, C.A., Pollina, C., Kaiya, H., Sakaguchi, H., and Takei, Y. (1997)Local synthesis of natriuretic peptides in the eel intestine.Biochem. Biophys. Res. Comm. 238: 817-822.[]
  • Links to GenBank Data: