One of the drawbacks to modern society is our more frequent exposure to noisy environments. This can make daily communicative tasks difficult, especially for those with hearing impairment, but it may also result in a cascade of changes throughout the auditory system. The auditory system has proven to be remarkably plastic, leading to the notion that our frequent exposure to “non-traumatic” noise could result in impaired auditory function. In contrast, employing noise to induce plastic changes within the auditory system could potentially result in more effective management options for hearing disorders such as tinnitus and hyperacusis. One of my primary research interests lie in exploring auditory plasticity associated with extended exposure to low or moderate levels of noise. Specifically, how these changes could negatively impact hearing ability, or could be leveraged to aid in the management of tinnitus or hyperacusis.
Clinically, I have experience in diagnostic audiology, hearing aid evaluations and programming, real-ear measures, tinnitus evaluations and management, electrophysiology testing, and clinical research. One of my professional goals is to aid in bridging the gap between scientific research and clinical practice.
Employment/ Professional Experience
Sheppard A, Hayes SH, Chen GD, Salvi RJ. (2013). Review of Salicylate-Induced Hearing Loss, Neurotoxicity, Tinnitus and Neuropathophysiology. Acta Italica. 2014;34:1-00nj
Sheppard AM, Chen GD, Salvi R (2015) Potassium ion channel openers, Maxipost and Retigabine protect against peripheral salicylate ototoxicity in rats. Hearing research 327:1-8.
Chen, G.D., Sheppard, A.M., Salvi, RJ. (2015) Noise Trauma Induced Plastic Changes in Brain Regions Outside the Classical Auditory pathway. Neuroscience.
Radziwon K, Hayes SH, Sheppard A.M., Salvi RJ (2015). Tinnitus: Clinical and Research Perspectives/Drug-induced tinnitus (89-109). San Diego, CA: Plural Publishing, Inc.
Ding, D., Jiang, H., Chen, G.D., Longo-Guess, C., Muthaiah, V., Sheppard, A., P.K., Tian, C., Salvi, R., Johnson, K.R. (2016). Progressive hearing loss caused by selective loss of inner hair cells in GGT1 deficient mice. Aging.
Sheppard, A., Chen, G.D., Salvi, R.J., (2017). Prolonged Low Level Noise Induced Plasticity in the Peripheral and Central Auditory System of Rats. Neuroscience.
Salvi, R., Sheppard, A. (2017). Is MR Scanner Noise a Significant Risk Factor for Hearing Loss? Radiology.
Sheppard, A., (2017). The “No Longer Hidden” Hearing Loss and Audiology: Bridging the Research-Clinic Gap. Canadian Journal of Audiology.
Sheppard, A., Zhao, D.L., Salvi, R., (2018). Isoflurane Impairs Cochlear Amplification in Rats. Journal of Otology. (under review)