A Century of Chemistry PhD Achievement

Grant E DuBois is an Organic Chemist (BS Chemistry and Mathematics / Capital University; PhD Organic Chemistry / SUNY at Buffalo; Postdoc / Stanford University). Grant was recipient of a Distinguished Alumnus Award / Capital University, was awarded entry to his high school Wall of Fame and is listed in Marquis Who’s Who.

Grant began his professional career with Dynapol Co. (sweetener research) and then joined Syva Co. (immunoassay development and fluorescent probe research). Subsequently, he joined Searle Pharmaceutical Co. (sweetener research) which led to the development of neotame. Grant then joined The Coca-Cola Co. where he was named the company’s first Research Fellow. Research led to 1) first 0-calorie frozen beverages, 2) first sweetener receptor positive allosteric modulators (Senomyx collaboration) and 3) GRAS approval of stevia sweetener rebaudioside A. In 2012, Grant joined stevia sweetener manufacturer Almendra, as CSO. Grant’s Almendra research led to a breakthrough formulation technology commercialized as System G™, markedly improving the tastes of all sweeteners. Concurrently, Grant served as VP Research for Crave Crush LLC and developed a gymnemic acid based dietary supplement for treatment of obesity and diabetes, commercialized as Sweet Defeat™. Grant is an inventor on about 100 patents and patent applications and author of approximately 80 publications.

Sweetness: Yesterday, Today and Tomorrow

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Mark E. Meyerhoff is the Philip J. Elving Professor of Chemistry Emeritus at the University of Michigan (UM).  He received his Ph.D. from SUNY-Buffalo in 1979 and joined the faculty at UM that same year. His research focuses on the development of new ion-, gas-, and bio-selective electrochemical/optical sensors. 

He also conducts research on the development of novel nitric oxide (NO) releasing materials/devices. He has authored > 430 papers over the past 46 years. He has received the ACS-Division of Analytical Chemistry Award in Electrochemistry (2003), the Society for Electroanalytical Chemistry’s Reilley Award (2006), the Ralph Adams Award in Bioanalytical Chemistry (2014), the American Chemical Society’s Award in Analytical Chemistry (2020), the Association of Analytical Chemists ANACHEM Award (2021), and the Talanta Medal (2023).

Enhancing the Biocompatibility of Intravascular Devices (Catheters, Sensors, etc.)

Just say YES to NO (Nitric Oxide) Releasing Materials

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Chemical sensors, societal value, and SUNY at Buffalo Chemistry - A Career.

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After completing a postdoc where I studied copper containing proteins with Professor E. I. Solomon at M.I.T. and Stanford University, I started as a research scientist at Genentech, Inc. During my 30+ year career I played key roles in the development human growth hormone (Nutropin), DNase (Pulmozyme), and anti-VEGF (Avastin and Lucentis), while also participating in the development of numerous other therapeutic proteins.

In 1989, I moved into protein purification process development, and in 1999, I started moving into management roles of increasing responsibility within the technical development organization. I became the VP of US Biologics Technical Development in 2010, responsible in the US for all cell culture, protein purification, protein formulation, and protein analytical development for clinical and commercial biologic products. I retired from Genentech in 2013.

From Bioinorganic Chemistry to Biotechnology: 50 Years of Learning