Bo-Hua Hu


Bo-Hua Hu.

Bo-Hua Hu


Bo-Hua Hu


Professional Positions

Associate Professor           
     Department of Communicative Disorders and Sciences, University at Buffalo 
Res. Assistant Professor  
     Center for Hearing and Deafness, University at Buffalo
Associate Professor          
Institute of Otolaryngology, Chinese PLA General Hospital 
Assistant Professor 
Institute of Otolaryngology, Chinese PLA General Hospital 
Dept. of Otolaryngology, Chinese PLA General Hospital


Ph.D. in Communicative Disorders and Sciences 
      University at Buffalo 
M.A. in Audiology
     University at Buffalo 
Ph.D. in Otolaryngology
     Postgraduate Medical School of PLA, Beijing
M.A. in Otolaryngology
     Postgraduate Medical School of PLA, Beijing
M.D. in Medical Science
     Second Military Medical University, Shanghai


For a list of all publications, see Google Scholar profile.

Zhang, C., Adler, H.J., Manohar, S., Salvi, R., Sun, W., Ye, M., Hu, B.H., 2022. Galectin-3 protects auditory function in female mice. Hearing Research. In press.

Riley, J., Hu, B.H., Bielefeld, E., 2022. Mild hearing loss in C57BL6/J mice after exposure to antiretroviral compounds during gestation and nursing. International Journal of Audiology. Pages 1-7. DOI: 10.1080/14992027.2022.2067081

Zheng, T., Huang, W., Yu, H., Hu, B.H., Song, P., McCarty, C.M., Lu, L., Jaster, J., Jin, G., Zhang, Y., 2022. gom1 Mutant Mice as a Model of Otitis Media. Journal of the Association for Research in Otolaryngology 23(2), 213-223.

Zhang, C., Frye, M.D., Riordan, J., Sharma, A., Manohar, S., Salvi, R., Sun, W., Hu, B.H., 2021. Loss of CX3CR1 augments neutrophil infiltration into cochlear tissues after acoustic overstimulation. Journal of Neuroscience Research. 99, 11, 2999-3020.

Zhao, T., Ma, P., Zhao, F., Zheng, T., Yan, B., Zhang, Q., Yuan, J., Hu, B., Yang, Y., Hu, J., Geng, R., Hu, B.H., Sun, T., Zheng, Q.Y., Li, B. 2021. Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene. J Neurosci Res. 99(10), 2743-2758

Zhao, T., Zheng, T., Yu, H., Hu, B.H., Hu, B., Ma, P., Yang, Y., Yang, N., Hu, J., Cao, T. 2021a. Autophagy impairment as a key feature for acetaminophen-induced ototoxicity. Cell death & disease 12, 1-19.

Zhang, C., Frye, M.D., Sun, W., Sharma, A., Manohar, S., Salvi, R., Hu, B.H. 2020. New insights on repeated acoustic injury: Augmentation of cochlear susceptibility and inflammatory reaction resultant of prior acoustic injury. Hear Res 393, 107996.

Zhuang, H., Yang, J., Huang, Z., Liu, H., Li, X., Zhang, H., Wang, J., Yu, S., Liu, K., Liu, R., Bi, M., Wang, J., Salvi, R., Hu, B.H., Teng, G., Liu, L. 2020. Accelerated age-related decline in hippocampal neurogenesis in mice with noise-induced hearing loss is associated with hippocampal microglial degeneration. Aging 12, 19493-19519.

Zheng, Q.Y., Kui, L., Xu, F., Zheng, T., Li, B., McCarty, M., Sun, Z., Zhang, A., Liu, L., Starlard-Davenport, A., Stepanyan, R., Hu, B.H., Lu, L. 2020. An Age-Related Hearing Protection Locus on Chromosome 16 of BXD Strain Mice. Neural Plast 2020, 8889264.

Hongchun Zhao, Yanfei Wang, Bo Li, Tihua Zheng, Xiuzhen Liu, Bo Hua Hu, Juan Che, Tong Zhao, Jun Chen, Maria Hatzoglou, Xiaolin Zhang, Zhaomin Fan and Qingyin Zheng. 2020. Role of Endoplasmic Reticulum Stress in Otitis Media. Front Genet . doi: 10.3389/fgene.2020.00495.

 Dong, Y., Zhang, C., Frye, M., Yang, W., Ding, D., Sharma, A., Guo, W., Hu, B.H. 2018. Differential fates of tissue macrophages in the cochlea during postnatal development. Hear Res 365, 110-126.

Frye, M.D., Zhang, C., Hu, B.H. 2018. Lower level noise exposure that produces only TTS modulates the immune homeostasis of cochlear macrophages. Journal of Neuroimmunology 323, 152-166.

Hu, B.H., Zhang, C., Frye, M.D. 2018. Immune cells and non-immune cells with immune function in mammalian cochleae. Hear Res 362, 14-24.

Zhang C, Sun W, Li J, Xiong B, Frye MD, Ding D, Salvi R, Kim MJ, Someya S, Hu B.H. Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea. Neuroscience. 2017;361:179-91. doi: 10.1016/j.neuroscience.2017.08.015. PubMed PMID: 28818524; PMCID: PMC5605466.

Xu Y, Yang WP, Hu BH, Yang S, Henderson D. 2017 Involvement of p53 and Bcl-2 in sensory cell degeneration in aging rat cochleae. Acta oto-laryngologica. 137(6):572-80.

Sheppard AM, Chen GD, Manohar S, Ding D, Hu BH, Sun W, Zhao J, Salvi R. Prolonged low-level noise-induced plasticity in the peripheral and central auditory system of rats. Neuroscience. 359:159-71. doi: 10.1016/j.neuroscience.2017.07.005. PubMed PMID: 28711622; PMCID: PMC5580356.

Book Chapters

Hu, B.H. 2011. Noise-induced structural damage to the cochlea. In: Popper, A.N., Fay, R.R., Henderson, D., Prell, C.L., (Eds), Springer Handbook of Auditory Research, Noise Induced Hearing Loss: Scientific Advances. Springer Science, New York. pp. 57-86.

Henderson, D., Hu, B.H., Bielefeld E. (2008) Patterns and Mechanisms of Noise-induced Cochlear Pathology. In Schacht, J., Popper, A.N. and Fay R.R. (Eds.), Auditory Trauma, Protection, and Repair. Springer. pp. 195-217.

Henderson, D., Hu, B.H., Bielefeld E., Nicotera, T.M. (2006) Cellular mechanisms of noise-induced hearing loss. In Campbell, K (Ed.), Pharmacology and Ototoxicity for Audiologists. Thomson Delmar Learning, pp. 216-229.

Hu, B.H., Henderson, D., Nicotera, T.M. (2003). Progression of outer hair cell death in the chinchilla cochlea following traumatic noise exposure. In: Simmons, D.D., Palmer, C., (Eds.), Seminars in Hearing.  New Frontiers in the Amelioration of Hearing Loss: Part 2 Hair Cell Development, Regeneration, Protection, and Rescue, Vol. 24. Theime Medical Publishers, New York. pp. 111-114.

Hu, B.H., Henderson, D., Liu, C.C., Zheng, X.Y., McFadden, S.L., Nicotera, T.M., Hight, N.G. (2001). Protection from impulse noise with R-PIA is dependent on the level of the noise and the duration of the treatment. In: Henderson, D., Prasher, D., Kopke, R., Salvi, R.J., Hamernik, R.P., (Eds.), Noise Induced Hearing Loss: Basic Mechanisms, Prevention and Control, 1st ed. Noise Res. Network Publications (nRn), London. pp. 203-213.

Nicotera, T.M., Henderson, D., Hu, B.H., Zheng, X.Y. 2001. Noise exposure and mechanisms of hair cell death. In: Henderson, D., Prasher, D., Kopke, R., Salvi, R.J., Hamernik, R.P., (Eds.), Noise Induced Hearing Loss: Basic Mechanisms, Prevention and Control, 1st ed. Noise Res. Network Publications (nRn), London. pp. 99-117.