Funding and Grants

1.

The Department of Biological Sciences supports the research of our faculty, postdoctoral scholars, graduate students, and undergraduates through funding obtained from many granting agencies, including both government and private foundations. Active and completed grants are listed on this page.

Updated March 6, 2024

Research Project Sponsor PI Period Amount
Translation Dysregulation in Metastatic Breast Cancer: Implications for Disease and Immunotherapy Outcomes
US Army Medical Research Acquisition Activity
Sarah E. Walker
3/1/2024 – 2/28/2027
$554,875.
Plant Terpenoids: Deciphering Metabolic Pathways and Improving Production in Microbes 
National Institute of General Medical Sciences (NIGMS)  
Zhen Q. Wang
9/1/2023 – 6/30/2028
$1,998,555.
PlantSynBio: Integrate Natural Product Biosynthesis into the Global Metabolic Network 
National Science Foundation (NSF)
Zhen Q. Wang
8/1/2023 – 7/31/2026 
$400,000.
Development of therapeutics for FOXG1 syndrome using patient-specific human iPSC and mouse models Simons Foundation Autism Research Initiative
Soo-Kyung Lee
4/1/2023- 3/31/2026 $1,500,000.
Parsing the central control of thirst and hunger using a rat model of diabetes insipidus
National Institutes of Health (NIDDK)
Daniels
8/17/2022– 5/31/2026
$2,117,234.
Molecular mechanisms of eukaryotic translational control National Institutes of Health Walker 4/1/2022-2/28/2027 $1,633,881.
Integrating paleogenomics, ecology, and geology to predict organism-environment coupled evolution during rapid warming and ice sheet retreat
National Science Foundation

PI: Lindqvist

Co-PIs: 
Jason Briner, Elizabeth Thomas, Corey Krabbenhoft 

2/1/2023-1/31/2027
$2,945,234. total
Sirtuins as rewiring points to evolve new responses to low NAD+ stress in yeast National Science Foundation Rusche 03/01/2020-02/28/2023 $750,000.
Transcription Factors Governing The Development Of Ghrh-Neurons NINDS/NIH Jae Lee  8/1/2021-7/31/2025 $547,873. anually;  $2.6M total award
Elucidating the role of protein arginine methylation in regulating RNA-binding protein function National Science Foundation Yu 5/1/2021-4/30/2025 $1,109,203.
Control of MAPK Signaling by Cell Polarity Proteins National Institute of General Medical Sciences Cullen 9/1/2011-3/31/2025 $212,500/year
Salivary proteome evolution as a framework to elucidate the mechanisms of functional change involving genomic structural variation National Science Foundation Gokcumen 3/1/2021 - 2/29/2024 $723,602
Cisco (Coregonus artedi) reference genome project: an integrative resource for management and restoration of Great Lakes coregonines Great Lakes Fishery Commission Krabbenhoft 1/1/2021 – 6/30/2023 $197,434
Genomic Architecture Underlying Biochemical Diversity and Molecular Convergence within the Carnivorous Plants National Science Foundation Albert, Co-PI
(PI: Tanya Renner, Penn State University).
Starts: 1 October 2020 $362,048 subaward of $975,421 
Discovering the molecular mechanisms that underlie the repeated evolution of gigantic tortoises NSF Lynch 9/1/2020-9/1/2023 $250,823
Construction and characterization of humanized FoxG1 mouse models FoxG1 Research Foundation Jae Lee 7/1/2020 - 6/30/2023 $400,000/year 
Molecular dissection of forebrain developmental deficits caused by mutations in human FoxG1 syndrome FoxG1 Research Foundation Soo Lee  7/1/2020 - 6/30/2023 $200,000/year 
Transcriptional regulators of motor columnar specification NINDS/NIH Soo Lee  4/1/2019 – 03/31/2024 $2,494,667
FoxG1-directed Gene network in forebrain development and FoxG1 syndrome  NINDS/NIH Soo Lee  6/1/2017 – 04/30/2022 $2,412,778
Roles Of Mll4-Complex In Development Of Hypothalamic Arcuate Neurons NIDDK/NIH Jae Lee 7/1/2020 -6/30/2021 $81,001
Transcription Factors Governing The Development Of Ghrh-Neurons NINDS/NIH Jae Lee 7/1/2020 - 6/30/2021 $558,250
Dissecting the in vivo role of glycogen synthase kinase-3 beta (GSK3b) in the function of kinesin-1 using CRISPR/Cas-1 NIH NINDS Gunawardena 7/1/2020—6/30/2022 $157,138/year
Developmental changes in gene expression in wild and hatchery-raised cisco (Coregonus artedi) U.S. Geological Survey Krabbenhoft 9/1/2019-8/31/2021 $70,000
Testing the Refugia Hypothesis in Southeast Alaska Using Paleogenetics and Glacial Chronology National Science Foundation Lindqvist 5/1/2019-4/30/2022 $542,156
Role of olivocochlear efferents in age-related hearing dysfunction National Inst on Deafness & Other Comm Disorders Xu-Friedman 7/9/2018-6/30/2023 $299,585
Evolutionary mechanics of adhesion complexes that mediate Amniote hearing Human Frontiers Science Program (HFSP) Lynch 8/1/2018-8/1/2022 $300,000
Evaluation of potential metallic compounds that activate taste receptor cells in the mouth Ajinomoto Company Incorporated Medler 8/2/2018-8/2/2021 $108,220
A novel therapeutic nano-vesicle for the clearance of axonal blocks to prevent Alzheimer's disease BrightFocus Foundation Gunawardena 7/1/2018-6/30/2021 $300,000
Gap Junction-Mediated Regulation of Nociceptive Sensory Signaling National Inst on Deafness & Other Comm Disorders Ferkey 12/1/2016-11/30/2021 $1,660,417
Activity-dependent regulation of auditory nerve synapses in the cochlear nucleus National Inst on Deafness & Other Comm Disorders Xu-Friedman 3/1/2017-2/28/2022 $1,674,771
Functional genomics of Great Lakes ciscoes (Coregonus spp); identifying genetic markers consistent with morphological differences Great Lakes Fishery Commission Krabbenhoft 5/1/2018-4/30/2022 $289,156
The adaptive variation of human skin: A comprehensive anthropological genetics examination of epidermal differentiation complex National Science Foundation Gokcumen 7/15/2017-6/30/2020 $377,886
Dynamics and allostery in protein-RNA regulation National Institutes of Health Gollnick 5/1/2017-2/29/2020 $580,658
Collaborative Research: Evolutionary trends and ecological drivers of eye reduction in bat flies (Hippoboscoidea) National Science Foundation Koudelka 3/15/2016-2/29/2020 $353,925
Collaborative Research: A Paleogenetic Survey of Late Quaternary Mammal Biodiversity in Southeast Alaska National Science Foundation Lindqvist 3/1/2016-8/31/2019 $150,000
Evolving contributions of the origin recognition complex (ORC) to subtelomeric chromatin National Science Foundation Rusche 8/25/2016-8/31/2019 $609,088
Translational control by the eIF4 factors National Institute of General Medical Sciences Walker 9/1/2015-8/31/2019 $745,668
Dimensions: Collaborative Proposal: Molecular, ecological and evolutionary dynamics of carbon fixation and diversification in Agavoideae (Asparagaceae) and Oncidiinae (Orchidaceae) National Science Foundation Albert 8/1/2014-12/31/2019 $477,624
The Amborella Genome: An Evolutionary Reference for Plant Biology National Science Foundation Albert 7/1/2010-9/30/2019 $909,066
Evolution of Silencing Proteins in Yeast National Science Foundation Rusche 9/1/2012-7/31/2017 $670,984