Nitasha Sehgal

PhD

Nitasha Sehgal.

Nitasha Sehgal

PhD

Nitasha Sehgal

PhD

Lecturer
Undergraduate Laboratory Instructor

Research Interests

Cell biology of the nucleus

Contact Information

202A Hochstetter Hall

Buffalo NY, 14260

Phone: (716) 645-2878

nsehgal@buffalo.edu

Office Hours

Friday, 11:00am to 12:00pm

Education

  • Postdoctoral Fellow, Department of Dermatology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
  • Ph.D., Department of Biological Sciences, University at Buffalo. Dissertation: Chromosome Territory Organization: A study of 3-D Topology and Interchromosomal Networks
  • MS, Department of Biological Sciences, University at Buffalo
  • MS (Hons), Department of Biochemistry, Panjab University, Chandigarh, India
  • BS (Hons), Department of Biochemistry, Panjab university, Chandigarh, India

Research and Teaching Statement

While I like basic research very much, I enjoy teaching. I feel that teaching, like learning, is a continuous process and evolves over time. With a long term goal to teach college students, I switched from pursuing research to undergraduate laboratory teaching. My role as an undergraduate lab instructor involves not only teaching, but also course improvement. I was involved in the development of a CRISPR lab, which was introduced to Bio 329 (Genetics laboratory) students in Fall 2017. I look forward to improving student laboratory learning experience.

Courses

BIO 200, Evolutionary Biology (Laboratory)

BIO 305, Fundamentals of Biochemistry

BIO 315, Fundamentals of Biochemistry (Course Coordinator)

BIO 329, Genetics Laboratory

BIO 370, Development Biology Laboratory

Selected Publications

  • Fritz AJ, Sehgal N, Pliss A, Xu J, Berezney R. Chromosome territories and global regulation of the genome. Genes Chromosomes and Cancer. 2019 Jul; 58(7):407-426
  • Sehgal N., Snyder G., and Hennessey T. 2019. Fundamentals of Biochemistry Lab Manual. Hayden-Mcneil/Macmillan Learning Curriculum Solutions, Plymouth, MI. 1st edition.
  • Sehgal N., Sylves M.E., Sahoo A., Chow J., Walker S.E., Cullen P.J., Berry, J.O. CRISPR Gene Editing in Yeast: An Experimental Protocol for an Upper-Division Undergraduate Laboratory Course. Biochem Mol Biol Educ. 2018 Nov; 46(6):592-601.  doi: 10.1002/bmb.21175. Epub 2018 Oct 12. 
  • Sehgal et al. Large-scale probabilistic 3D organization of human chromosome territories. Hum Mol Genet. 2016 Feb 1;25(3):419-36. doi: 10.1093/hmg/ddv479. This article has been recommended by Faculty of 1000. A figure of this article also made the journal cover page for the issue it was published in.
  • Sehgal et al. Reorganization of the interchromosomal network during keratinocyte differentiation. Chromosoma. 2016 Jun;125(3):389-403. doi: 10.1007/s00412-015-0546-5. Epub 2015 Oct 21.
  • Sehgal et al. Gene density and chromosome territory shape. Chromosoma. 2014 Oct;123(5):499-513. doi: 10.1007/s00412-014-0480-y. Epub 2014 Aug 9.
  • Chen, Z., Chen, D., Ding, H., Huang, Z., Li, Z., Sehgal, N., ... & Xu, J. (2016, December). Finding rigid sub-structure patterns from 3D point-sets. In Pattern Recognition (ICPR), 2016 23rd International Conference on (pp. 1725-1730). IEEE.
  • Chen, Z., Ding, H., Chen, D., Wang, X., Fritz, A., Sehgal, N., ... & Xu, J. (2015, September). Mining k-median chromosome association graphs from a population of heterogeneous cells. In Proceedings of the 6th ACM Conference on Bioinformatics, Computational Biology and Health Informatics (pp. 47-56). ACM.