Chemical biology, medicinal chemistry, structure-guided drug design, protein biochemistry, structural biology, cancer biology, protein kinases, allosteric inhibitors, targeted protein degradation, bioinorganic chemistry, redox biology, and bioorthogonal chemistry.
The Heppner lab studies molecules, proteins, and cells to develop innovative solutions to persistent challenges in human health. We apply an integrative approach through a combination of medicinal chemistry, biochemistry, cellular and molecular biology, biophysics, and structural biology to discover and design novel therapeutics and molecular tools for biological applications. Our research is equally directed to understand protein structural and mechanistic essentials that control biochemical processes important in cancer biology and other diseases. Current areas of interest include:
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