Analytical Chemistry; Analytical Separations; Microextraction Technologies; Fate and transport of emerging contaminants in heterogeneous environmental systems; Micropollutants exposure to human and wildlife; Use of natural polymers for separations; Bioanalytical Chemistry; PFAS preconcentration and quantification in complex media; Target and non-target analysis of environmental contaminants; Hyphenation of microextraction technologies to mass spectrometry; Fundamentals of analytical separations; Green Analytical Chemistry
The Gionfriddo laboratory contributes to the field of analytical chemistry with findings and new technologies for separation, preconcentration, and detection of micropollutants in complex samples. We tackle questions related to the distribution and partitioning of micropollutants in the environment and biological systems using microseparations for preconcentration and mass spectrometry for structural identification and detection at ultra-trace levels. These findings, in turn, provide critical tools to address the link between environmental contamination and human exposure and lead to a better understanding of routes of exposure and the elusive effects of xenobiotics in living systems. We use miniaturized extraction methodologies (e.g. Solid Phase Microextraction and related techniques) coupled to gas and liquid chromatography or directly hyphenated to mass spectrometry.