Emanuela Gionfriddo


Emanuella Gionfriddo headshot.

Emanuela Gionfriddo


Emanuela Gionfriddo


Research Interests

Analytical Chemistry; Analytical Separations; Microextraction Technologies; Fate and transport of emerging contaminants in heterogeneous environmental systems; Micropollutants exposure to human and wildlife; Use of natural polymers for separations; Bioanalytical Chemistry; PFAS preconcentration and quantification in complex media; Target and non-target analysis of environmental contaminants; Hyphenation of microextraction technologies to mass spectrometry; Fundamentals of analytical separations; Green Analytical Chemistry

Professional Appointments

  • Associate Professor, 2023 - present
    University at Buffalo, Buffalo, NY
  • Associate Professor, 2023
    University of Toledo, Toledo, OH
  • Assistant Professor, 2018-2023
    University of Toledo, Toledo, OH


  • Research Associate, 2017
    University of Waterloo, ON, Canada
  • Post Doctoral Fellow, 2014-2017
    University of Waterloo, ON, Canada
  • Ph.D., Analytical Chemistry, 2010-2013
    University of Calabria, Department of Chemistry and Chemical Technologies, Italy
  • M.Sc., Chemistry, 2008-2010
    University of Calabria, Department of Chemistry and Chemical Technologies, Italy
  • B.Sc., Chemistry, 2005-2008
    University of Calabria, Department of Chemistry and Chemical Technologies, Italy

Other Experience

  • Chair-Elect, Analytical Chemistry Subdivision of the American Chemical Society on Chromatography and Separation Chemistry, 2023-present
  • Early Career Board, Analytical Chemistry, American Chemical Society, 2024-present
  • Editorial Advisory Board, Analytica Chimica Acta , Elsevier, 2023-present
  • Editorial Advisory Board, Analytical and Bioanalytical Chemistry,  Springer, 2023-present
  • Editorial Advisory Board, Green Analytical Chemistry, Elsevier, 2021-present
  • Editorial Advisory Board, Advances in Sample Preparation, Elsevier, 2021-present
  • Attorney General Yost's Environmental Council of Advisors, Ohio Attorney General Office, Columbus, OH, 2020-2023
  • Founding member of the Dr. Nina McClelland Laboratory for Water Chemistry and Environmental Analysis, The University of Toledo, 2019
  • Institutional Coordinator of ACS Project SEED, University of Toledo, 2019-2023

Honors and Awards

  • CAREER Award, National Science Foundation, 2022
  • 2024 Chinese American Chromatography Association Young Investigator Award, 2024
  • 2023 Eastern Analytical Symposium Young Investigator Award, Eastern Analytical Symposium, 2023
  • 2023 LCGC Emerging Leader in Chromatography Award, LCGC North America, 2023
  • 2022 Satinder Ahuja Award for Young Investigators in Separation Science, American Chemical Society -Analytical Chemistry Division, 2022
  • 2022 UToledo President's Award for Excellence in Creative and Scholarly Activities, The University of Toledo, 2022
  • Rising Star of Separation Science, LC-GC Europe and Asia, 2021
  • UTC Excellence in Sample Prep Award, North American Chemical Residue Workshop- NACRW, 2018
  • Young Author Price - ExTech2018-International Symposium on Advances in Extraction Technologies, 2018


The Gionfriddo laboratory contributes to the field of analytical chemistry with findings and new technologies for separation, preconcentration, and detection of micropollutants in complex samples. We tackle questions related to the distribution and partitioning of micropollutants in the environment and biological systems using microseparations for preconcentration and mass spectrometry for structural identification and detection at ultra-trace levels. These findings, in turn, provide critical tools to address the link between environmental contamination and human exposure and lead to a better understanding of routes of exposure and the elusive effects of xenobiotics in living systems. We use miniaturized extraction methodologies (e.g. Solid Phase Microextraction and related techniques) coupled to gas and liquid chromatography or directly hyphenated to mass spectrometry.

Recent Publications

  • Godage N.H., Qian S.S., Cudjoe E., Gionfriddo E.*, "Enhancing Quantitative Analysis of Xenobiotics in Blood Plasma through Cross-Matrix Calibration and Bayesian Hierarchical Modeling", ACS Measurement Science Au, in press, https://doi.org/10.1021/acsmeasuresciau.3c00049
  • Williams M.L., Olomukoro A.A., Emmons R.V., Goodage N.H., Gionfriddo E*., "Matrix Effects Demystified: Strategies for Resolving Challenges in Analytical Separations of Complex Samples", Journal of Separation Science, 2023, 2300571 10.1002/jssc.202300571
  • Emmons R.V., Fatigante W., Olomukoro A.A., Musselman B., Gionfriddo E.*, “Rapid Screening and Quantification of PFAS Enabled by SPME-DART-MS”, Journal of the American Society for Mass Spectrometry 2023, 34, 9, 1890–1897, 10.1021/jasms.3c00088
  • Olomukoro A.A., DeRosa, C., Gionfriddo E.*, “Investigation of the Adsorption/Desorption Mechanism of Perfluoroalkyl Substances on HLB-WAX Extraction Phases for Microextraction”, Analytica Chimica Acta 20231260, 341206, https://doi.org/10.1016/j.aca.2023.341206
  • Godage N.H., Cudjoe E., Chau T., Gionfriddo E.*, “Quantitative Determination of Pesticides in Human Plasma using bio-SPME-LC–MS/MS: A Robust Tool to Assess Occupational Exposure to Pesticides”, Analytical and Bioanalytical Chemistry, 1-12, 2023, https://doi.org/10.1007/s00216-023-04589-8
  • Claus M.J., Gionfriddo E., Monahan J., Whelan R.J., Vitha M.F. *, “Threshold Concepts in Analytical Chemistry”, Journal of Chemical Education, 2023, 100, 2, 427–431 https://doi.org/10.1021/acs.jchemed.2c00674
  • Emmons R.V., Karaj E., Cudjoe E., Bell D., Tillekeratne L., Gionfriddo E.*, “Leveraging Multi-mode Microextraction and Liquid Chromatography Stationary Phases for Quantitative Analysis of Neurotoxin β-N-Methylamino-L-alanine and Other Non-proteinogenic Amino Acids”, Journal of Chromatography A, 2022, 1685, 463636 https://doi.org/10.1016/j.chroma.2022.463636
  • Emmons R.V., Sunder G.S.S., Liden T., Schug K.A., Asfaha T.Y., Lawrence J.G., Kirchhoff J.R., Gionfriddo E.*, "Unraveling the Complex Composition of Produced Water by Specialized Extraction Methodologies", Environmental Science & Technology 2022. https://doi.org/10.1021/ACS.EST.1C05826
  • Godage N.H., Gionfriddo E.*, "Biocompatible SPME Coupled to GC/MS for Analysis of Xenobiotics in Blood Plasma", Journal Of Chromatography B-Analytical Technologies In The Biomedical And Life Sciences 2022, 1203. https://doi.org/10.1016/j.jchromb.2022.123308
  • Olomukoro A.A., Emmons R.V., Godage N.H., Cudjoe E., Gionfriddo E*, “Ion Exchange Solid Phase Microextraction Coupled to Liquid Chromatography/Laminar Flow Tandem Mass Spectrometry for the Determination of Perfluoroalkyl Substances in Water Samples”, Journal of Chromatography A 2021, 1651. https://doi.org/10.1016/j.chroma.2021.462335