Nanophotonics, Nonlinear Optical Effects in Organic and Organic: Inorganic Hybrids, Multiphoton Processes and Applications, Metaphotonics and Chiral Photonics, Biophotonics, Nanomedicine, Sensor Technology, Energy Materials, Nanomagnetics
Nanophotonics program consists of three parts: (i) nanoscale confinement of radiation to control the propagation properties of radiation and its interaction with matter; (ii) nanoscale confinement of matter and domains to control the optical resonances (band gap) and excitation dynamics; and (iii) nanoscale confinement of photoprocesses to control spatial confinement of optically induced changes useful for optical memory applications and nanofabrication.
Nonlinear Optics research program represents study of new nonlinear optical phenomena, design and development of nonlinear optical polymers, study of their ultrastructure, and dynamics of nonlinear optical interactions. One area is the study of photorefractivity which is a second order effect and various third-order nonlinear optical manifestations in organic: inorganic hybrids as well as in artificially nanostructured (such as photonic crystal) media.
Multiphoton Processes and Applications focuses on the development of multifunctional structures with enhanced two-photon, three-photon and four-photon absorption cross-sections as well as efficient up-converted emissions. Theoretical modeling and synthesis are used together to produce such materials.
In the metaphotonics and Chiral Photonics a novel chemical approach of using coupled electric and magnetic resonances in a chiral medium to achieve negative refraction is used; our approach uses molecular chirality, amplification of chirality using supramolecular organizations and inclusions of plasmonic and excitonic nanostructures.
In the area of Biophotonics, biosensing, the focus is intracellular sensing using a variety of molecular probes and nanoprobes; another area of analyte and bacterial detection being developed is a compact advanced multiparameter flow cytometer providing some unique capabilities for clinical diagnostics; another area of activity is the use of laser tweezers and scissors for probing cellular interactions and producing biological manipulation. A major direction in brain research, pursued in our lab, is neurophotonics, where we apply photoresponsive materials for functional mapping of brain using optical and photoacoustic imaging. We also use optically guided and tracked nanoformulations to treat Alzheimer, as well as optogenetic stimulation and microglia activation to enhance brain function.
Some of the key areas of our nanomedicine program are: Nanoparticles for Multimodal Imaging and Novel Optical Diagnostics; Nanoclinics for Diagnostics and Targeted Therapy; New Modalities of Photodynamic Therapy; Non-Viral Gene Therapy.
The program in the Energy Materials area focuses on development of novel nanostructured materials and device engineering for energy application.
A major emerging area is nanomagnetics utilizing magnetic nanoparticles, which are surface-functionalized, paramagnetic or ferromagnetic structures and are linked to photonic probes.